The Mighty Throw Barbarian Endgame Build in Diablo 4 revolves around the Mighty Throw skill, which becomes a spammable screen-clearing ability with the help of the unique item The Third Blade.
Core Skills:

See in Action
Recommended Gear
Overview
Affixes
Tempering
Runes & Gems
Special
Unique helm
Ugly Bastard Helm
Mythic armor
Shroud of False Death
Unique gloves
Bane of Ahjed-Den
Unique pants
Tibault's Will
boots
Relentless Berserker's Aspect
bludgeoning weapon
Aspect of Delayed Extinction
Unique dual-wield weapon 1
The Third Blade
amulet
Aspect of Encroaching Wrath
ring 1
Bold Chieftain's Aspect
Mythic ring 2
Ring of Starless Skies
Mythic slashing weapon
The Grandfather
dual-wield weapon 2
Aspect of Herculean Spectacle
Selected Boss Powers
Wandering Death's Chest Beam
Main Power Slot
Sinerat's Flames
Power Modifier Slot
Harbinger of Hatred's Volley
Power Modifier Slot
Belial's Eye Beams
Power Modifier Slot
Boss Powers is a new seasonal mechanic introduced in Season 8. More information about it and all available Boss Powers can be found in the Wiki.
Selected Sills
Summary
Skill Tree
Basic
1
Enhanced Bash
Core
1
Violent Whirlwind
3
Pressure Point
3
Warpath
Defensive
1
Enhanced Rallying Cry
1
Enhanced Challenging Shout
3
Imposing Presence
3
Martial Vigor
1
Outburst
1
Tough as Nails
Brawling
5
Power War Cry
3
Booming Voice
1
Aggressive Resistance
3
Prolific Fury
Weapon Mastery
5
Warrior's Mighty Throw
3
Pit Fighter
3
Slaying Strike
1
Thick Skin
3
Counteroffensive
Ultimate
5
Supreme Wrath of the Berserker
3
Wallop
3
Brute Force
3
Heavy Handed
Key Passive
1
Unbridled Rage
Selected Expertise
Two-handed Axe
Main Bonus:
+10.0% increased damage to Vulnerable enemies.Additional Bonus at Rank 10:
+10% increased Critical Strike Chance against Vulnerable enemies.Mercenaries
HiredSubo
ReinforcementRaheir
Selected SkillBastion
Selected ConditionWhirlwind
Selected Paragon
Summary
All Boards
Board & Glyph Pairs
Starting Board
Crusher
Blood Rage
Ire
Decimator
Might
Bone Breaker
Challenger
Weapons Master
Dominate
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